This drama tells the story of the Seijin Shinkansen Hospital, located in a small alley in Kabukicho. Because of the local relationship, most of the patients who come to the emergency room are poor vagrants, foreigners, gigolos, prostitutes, etc., which are different from ordinary hospitals and have special backgrounds. At this time, a mysterious American former military doctor, Yoko Nishi Freeman (played by Eiko Koike) suddenly arrived. Then, Gao Fengxiang (played by Taiga Nakano), a cosmetic dermatologist working in the hospital of his elderly uncle, met her, and the gears began to turn.