This film is the sequel to "Sister Act" in 1992. Delos (Whoopi Goldberg) has become a famous singer in Las Vegas, and the nuns who shared the joys and sorrows with her in the previous episode have also been transferred to a community school. However, the children in this community school are a big trouble. They are naughty and are incompatible with the traditional nuns who abide by the rules. They either ignore the nuns' naps or wake up to make trouble and destroy them, which gives the nuns a headache. The helpless nuns had to ask Delos to come out again to discipline these children. The children were naturally dissatisfied when they saw Delos. They ignored her and came up with all kinds of tricks to tease her. However, the students soon learned how powerful Delos was. No matter what they did to her, Delos could always "treat them in their own way" in the end. In this way, everyone became obedient to Delos's discipline, and even the most naughty children realized how powerful she was. This is the first time that the kids have a purpose to participate in a competition. But this time, Delos's identity becomes a problem again...