In the future, the military developed a drug to enhance the combat capability of soldiers, but it backfired and caused a large number of people to be infected with the failed experimental preparations, and thus a group of cyborgs with bodies different from ordinary people were born. The military built a huge isolation building and developed the ultimate weapon to deal with cyborgs. So the cyborg organization sent a female warrior, Violet (Milla Jovovich), to sneak into the military and snatch the ultimate weapon by violence. Violet was curious and opened the package of the ultimate weapon on the road and found that there was a boy (Cameron Bright) inside. It turned out that the boy had blood antigens that could destroy cyborgs. Violet believed that blood antigens could also return cyborgs to human form. Dissatisfied with the organization's rough solution, she decided to betray and embarked on a desperate journey to avoid the military and the cyborg organization with the boy who called himself "No. 6". Behind the boy, there are even bigger secrets that have not yet been revealed.