The earth is the home of human beings. While supplying, it is also being plundered. When the earth's endurance reaches its limit, what will be the fate of mankind? In recent days, there have been many bizarre deaths in several major cities in the United States, and the scene of the incident is bloody and weird. How did these people die? Suicide or homicide? And why? Everything is in the fog. Elliot (Mark Wahlberg) is a middle school teacher studying natural sciences. This series of events caught his attention, and he felt that everything was not a coincidence. A larger-scale human death event occurred, and death was like a virus spreading among citizens. For a time, the population in the city was almost extinct. Elliot, his wife Alma (Zooey Deschanel) and a group of friends drove a car to start their escape. What exactly are they trying to avoid? Even they themselves don't know.