For Aubrey (Amber Tamblyn), the death of her sister Karen (Sarah Michelle Gellar) is full of doubts. Two years ago, Karen went to Japan to study. Not long after, Aubrey's family received the bad news that Karen was locked up in a mental hospital. Now, the once kind and beautiful sister has become a cold corpse. Aubrey firmly believes that there must be something strange, so she and Ethan (Edison Chen), a reporter who specializes in reporting supernatural events, teamed up to investigate the curse in the old house. At the same time, several bizarre deaths occurred around the world, and the deceased were inextricably linked to the curse. Is the curse really so pervasive? Who is behind this powerful force?