Gangster Joe Cabot (Lawrence Tierney) and his son "Good Guy" Eddie (Chris Penn) gathered six robbers to rob a batch of natural diamonds from a jewelry store. The six people did not know each other, and they did not even know each other's names. In order to keep secrets, Joe named the six people Mr. White (Harvey Keitel), Mr. Orange (Tim Roth), Mr. Gold (Michael Madsen), Mr. Pink (Steve Buscemi), Mr. Brown and Mr. Blue, and stipulated that they could not reveal any private matters to each other. During the robbery, the six were ambushed by the police, and Mr. Blue and Mr. Brown died on the spot. Mr. White took the seriously injured Mr. Orange back to the scheduled gathering place - a warehouse. After a while, Mr. Pink, "Good Guy" Eddie and Mr. Gold also came here and captured a policeman alive. Several people recalled the scene at the time of the crime and concluded that one of the six must have informed the police. In order to find out the informer, everyone interrogated and tortured the policeman, but still could not get the truth. Several people who did not know each other began to suspect each other, and the development of things completely deviated from the preset track.