A hurricane is hitting New Orleans, USA, and a critically ill old woman opens her sleepy eyes. The old woman's name is Daisy (Cate Blanchett), and she asks her daughter Caroline (Julia Ormond) to read a diary for her. The author of this diary is Benjamin Button (Brad Pitt). Benjamin was born at the end of World War I, but he was born like an old man and was regarded as a monster by his father and abandoned in a nursing home. Benjamin lives with the elderly in the nursing home. But no one expected that Benjamin would develop in the opposite direction - getting younger and younger! Maybe "getting younger and younger" is the dream of some people, but Benjamin, who really grew up like this, has troubles and happiness that others cannot understand. Through half a century of world changes, Benjamin is in it and feels what others cannot feel. Why did his mother let him read this diary? What is the relationship between Benjamin Button and his mother? Caroline fell into deep doubts and curiosity.