Everything comes from the loneliness that is everywhere. When loneliness spreads to the top of the head and it is hard to breathe, the outdated TV star Bob Harris (Bill Murray), the married Charlotte (Scarlett Johansson), and the young and beautiful movie actress Kelly (Anna Faris) meet in Tokyo by chance. In this strange city that is not their hometown, they meet in a luxury hotel, suffer from insomnia and accompany each other. On the one hand, life seems to become colorful, but on the other hand, it gradually becomes lost. Can the outdated star and the married Charlotte meet the challenge of their changing thoughts and relationships? Break through the loss or get stuck in it, let us find the answer together.