November 22 is the 50th anniversary of the assassination of former US President John F. Kennedy. This film is a tribute to the incident by the National Geographic Channel. TV celebrity Rob Lowe plays former US President Kennedy in this film, Ginnifer Goodwin from "Legend" plays Kennedy's wife and former US First Lady Jacqueline, Will Rothhaar plays Kennedy's assassin Lee Harvey Oswald (Note: there is still much controversy among historians), and Michelle Trachtenberg from "Gossip Girl" plays Oswald's wife and former Soviet immigrant Marina. The film has been translated into 48 languages and broadcast in 171 countries and regions around the world. This film is the second film in the National Geographic Channel's "Assassination" series of documentary films. The previous film "The Assassination of Lincoln" has received good reputation.