1989, Japan. One hundred years after the final battle between Jonathan Joestar and DIO, DIO is resurrected. At the same time, Joseph's grandson, Jotaro Kujo, discovers that he has the ability of Yubo Ripple (Stand). DIO's resurrection affects his mother who has no Stand resistance and falls into critical condition. In order to save his mother who is on the verge of death, Jotaro and Joseph set out for DIO's place - Egypt.