That night, in a large house in Weizhou, a dishevelled woman climbed out of bed with a bloody dagger in her hand, and the owner Diao Sihu was killed on the spot... Another night, Guangzhou's richest man Xu Jian wanted to push a woman onto the bed, but found that the god of death was waving at him... Chizhou's wealthy businessman Zhou Qi married a concubine that night, but was found to have been killed by a random knife the next day... Bao Zheng (played by Jin Chaoqun) was pondering. He was on a tour in Chizhou and encountered Zhou Qi's case. During the investigation, he found a case within a case - the three dead seemed to be strangers, but they all died on their wedding night, and the brides disappeared after the bloodbath. What's even more strange is that the dead were all wealthy businessmen who were fond of women, and all died in their bedrooms, and the fatal cause was not knife wounds, but the poison of the black widow spider. Bao Zheng went to Guangzhou to visit his relatives and started to investigate the case of the poisonous spider. He found that the three dead were sworn brothers in Yangzhou. The richest men in the area, Ba Renjie (played by Lu Yilong) and Ba Renfeng (played by Yang Zhongen), were also in the same group. The Ba brothers even colluded with Cui Lu (played by Wu Ma), the prefect, to obstruct the investigation. At this time, a new prostitute named Haitang (played by Zhen Xiuzhen) who was both beautiful and talented came to Guangzhou Wanhua Tower, which attracted the lustful Ba Renjie. On this day, Haitang and her maid Qiu'er were molested in the street. Fortunately, Zhan Zhao (played by Jiao Enjun) rescued them. Zhan was fascinated by the cold and beautiful Haitang, and later learned that the other party was originally a famous prostitute in the brothel. Zhan Daxia, who was unable to relieve the pain of lovesickness, proposed to Haitang, but she had already put her daughter's private love aside and was willing to feed the poisonous spider with her blood to avenge an unsolved case twelve years ago...