Harry (Jared Leto) and Marianne (Jennifer Connelly) love each other and dream of opening a clothing store and having a better tomorrow. However, they are inseparable from drugs and want to make their first pot of gold by selling drugs. Harry's mother is a complete TV fan. Her biggest dream is to be on TV. She swallows diet pills regardless of her old age. Due to the drug ingredients in the drugs, she gradually became addicted. Harry's friend Dillon (Marlon Wayans) is also an addict. In order to make a lot of money, he joined the underworld. For their dreams, they worked hard, but they were deeply trapped in drugs step by step. Harry's arm was cut off due to drug injection infection; Marianne sold her body and self-esteem for drugs; Harry's mother was eventually admitted to a mental hospital and tortured; Dillon was imprisoned. When the vision becomes blurred and the dream calls in the distance, how should the lost people comfort their souls?