In 2007, there was an abnormal disturbance in the basic science of the earth. For a time, the scientific community was in turmoil and people were in panic. A scientist who committed suicide bizarrely, a countdown that was almost miraculous, a secretive science border, and a mysterious "Three-Body" game... Nano scientist Wang Miao was brought to the Joint Operations Center by police officer Shi Qiang and sneaked into an organization called "Science Border" to assist in the investigation. In the fog, Wang Miao came into contact with an organization called ETO and found that its behind-the-scenes commander was Ye Wenjie, the mother of scientist Yang Dong who committed suicide. As ETO and the Operations Center continued to play games back and forth, Wang Miao and Shi Qiang gradually determined that the world in the "Three-Body" game really existed. The origin of all the events was the desperate life-and-death struggle between two civilizations for living space. With the joint efforts of the Joint Operations Center and scientists, Wang Miao, Shi Qiang and others strengthened their beliefs, rekindled their hopes, and led everyone to continue to prepare for a desperate struggle with the invading Trisolarans in the future.