Private detective Dylan Doug (Brandon Routh) is a man with extraordinary abilities. For some reason, he huddled in a corner of the city, living an anonymous life and trying not to attract the attention of others. One day, the super-rich Alf committed suicide, but his daughter believed that her father was murdered. Dylan came to Alf's residence at the request of his friend Marcus (Sam Huntington), but rejected the case. Shortly thereafter, Marcus died at home. The death of his friend touched Dylan greatly, so he accepted the commission about Alf again. After investigating the scene, he concluded that Alf died at the hands of a female werewolf. Dylan followed the clues to investigate in depth, and gradually put himself in great danger... This film is adapted from Tiziano Sclavi's comic series "Dylan Dog".