On September 25, Beijing time, ABC's heavyweight medical drama will return to our sight with a two-hour special. The questions about Izzie and George's stay or departure left at the end of the last season will be answered one by one in the return episode. Thanks to Katherine Heigl's frank remarks, we have roughly learned the fate of the two main characters in the play. Izzie will survive, and George will bid farewell to the audience. And because of TR Knight's contract issues, George may not appear in the sixth season with new shots, and the opening will only be replaced by a coffin. ABC TV also confirmed that TR Knight, who plays George, will not become a regular actor in the sixth season. On the contrary, Jessica Capshaw, who plays pediatrician Arizona Robbins, will be fortunate to become a regular actor in the sixth season. It can be predicted that the scenes of his homosexual relationship with another main character Callie in the play will also be lengthened.