In the late Qing Dynasty, the An Mansion in Beijing was a hereditary medical family. When An Jihe and his wife Qin took over, they made a sensation in the medical community because they prepared a miraculous recipe "Resurrection Pill" that could cure all diseases and prolong life, which attracted competition from all parties. A year after An Jihe's death, the "Resurrection Pill" was requisitioned by the court, which caused a catastrophe that destroyed his family and even affected his married daughter An Tianlan, causing her husband to die in vain. She fled to Jiangnan when she was pregnant and gave birth to her daughter Fang Xiruo who could not speak. Because of her family's decline, Fang Xiruo suffered torture and difficulties in her growth. Eighteen years later, Fang Xiruo was involved in a complex and difficult emotional entanglement. After experiencing the unjust extermination of her family, the abuse of her mother and daughter in exile, and the hardships of her life, she gradually unraveled her own confusing life experience and finally revealed the secret of the family's "Resurrection Pill".